Ugur Aferin

Dr. Ugur Aferin is a urological surgeon at Istanbul Florence Nightingale Hospital. He uses robotic and minimally invasive surgery for complex urological conditions. Dr. Aferin contributed to research on mitochondrial DNA as a potential biomarker for prostate cancer.

Specialization and Surgical Focus

Dr. Aferin treats conditions affecting the urinary tract and male reproductive system. He performs surgical treatment for localized prostate cancer and muscle-invasive bladder cancer. The doctor utilizes the Da Vinci robotic system to perform precise prostatectomies and nephrectomies. This technology allows for smaller incisions, reduced blood loss, and faster patient recovery.

He also treats complex cases of testicular torsion and high-flow priapism in children. Testicular torsion is a surgical emergency where the spermatic cord twists and cuts off blood supply to the testicle. Priapism is a prolonged, often painful erection that requires immediate medical intervention to prevent tissue damage.

Core Procedures

• Robotic da Vinci prostatectomy and adenomectomy
• Robotic and standard nephrectomy
• Holmium Laser Enucleation of the Prostate (HoLEP) — a procedure using lasers to remove prostate tissue obstructing urine flow
• Bladder removal with reconstruction
• Transurethral resection of the bladder (TURB)
• High-intensity focused ultrasound ablation (HIFU)
• Varicocelectomy and embolization of varicocele

Conditions Treated

• Prostate, bladder, and testicular tumors
• Benign prostatic hyperplasia (BPH)
• Urinary incontinence and bladder outlet obstruction
• Urolithiasis (kidney stones) and urethral strictures
• Erectile dysfunction and Peyronie's disease
• Male infertility issues, including azoospermia

Academic Research and Publications

Dr. Aferin is active in clinical research and has authored numerous peer-reviewed articles. He contributed a chapter on muscle-invasive bladder cancer to the 2022 book Current Perspective in Urooncology. His research explores diagnostic biomarkers and urodynamic patterns to improve patient outcomes. Additionally, he frequently presents his findings at international and national urological congresses.

Selected Peer-Reviewed Works

• "Are Elevated Mitochondrial DNA Fragments in Prostatic Inflammation a Potential Biomarker for Prostate Cancer?" – Archivio Italiano di Urologia e Andrologia, 2023
• "Urodynamic Curve Patterns May Predict Female Bladder Outlet Obstruction and Detrusor Underactivity" – Urology, 2022
• "Unusual Presentation of Classical Kaposi Sarcoma: Penile Involvement in an HIV Seronegative Patient" – European Journal of Medical Case Reports, 2023
• "Association Between Prostate Biopsy Results and Serum Vitamin D Levels" – Bulletin of Urooncology, 2021
• "A Case Report of Pediatric High-Flow Priapism: The Management of a Rare Condition" – European Journal of Medical Case Reports, 2021
• "Massive Inguinoscrotal Bladder Hernia and Bladder Tumor: A Very Rare Case" – J Urol Surg, 2018
• "Testicular Torsion: Experience in a Tertiary Urology Referral Centre" – Journal of Urological Surgery, 2021
• "Surgical Treatment in Localized Prostate Cancer" – Cancer Agenda Journal, 2022

Professional Background

Dr. Aferin has been an appointed Faculty Member since 2022. He completed his medical degree and urology doctorate at Istanbul University, Cerrahpaşa Faculty of Medicine. His training involved residency work in tertiary urology referral centers. He currently provides in-person care and online consultations for domestic and international patients.

Education and Training

• 2008–2014 – Istanbul University, Cerrahpaşa Faculty of Medicine – Medical Degree
• 2015–2020 – Istanbul University–Cerrahpaşa, Faculty of Medicine – Doctorate in Urology